Diclogesic 12.5 mg Analgesic and Antipyretic 10 Suppositories
Diclogesic 12.5 mg is a rectal suppository containing diclofenac sodium, a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce fever, and ease inflammation in conditions such as arthritis, muscle pain, and post-surgical pain. It works by inhibiting cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis, which alleviates pain and inflammation. Suitable for children over 1 year and adults.
Active Ingredients and Mechanism of Action
- Diclofenac Sodium (12.5 mg): Inhibits COX-1 and COX-2, reducing prostaglandin synthesis, pain, and inflammation. May also inhibit neutrophil aggregation, chemotaxis, and proinflammatory cytokines.
Other Ingredients
Suppository base (e.g., witepsol or fatty base), as per standard suppository formulations.
Key Features
- Pain Relief: Effective for mild to moderate pain in muscles, joints, and teeth.
- Anti-Inflammatory: Treats arthritis, sprains, and sports injuries.
- Antipyretic: Helps control fever.
- Suitable for Children and Adults: Safe dose for children over 1 year under medical supervision.
Indications
- Relieving pain and inflammation in arthritis (rheumatoid, gout, ankylosing spondylitis).
- Treating back pain, sprains, strains, sports injuries, and fractures.
- Managing pain and inflammation post-dental or minor surgery.
- Controlling fever.
- Treating tendon conditions like tendonitis.
Product Benefits
- Rapid Pain Relief: Alleviates pain and inflammation within hours.
- Fever Reduction: Effectively lowers body temperature.
- Convenient Use: Suppositories provide quick absorption without swallowing.
- Child-Friendly: Low dose safe for children over 1 year under medical guidance.
How to Use
- Lie on one side with knees pulled up toward the chest.
- Gently insert the suppository (pointed end first) into the rectum with your finger.
- Push the suppository as far as possible.
- Lower your legs and stay still for a few minutes to allow absorption.
- Press buttocks together if you feel the urge to expel the suppository.
- Wash hands thoroughly after use.
- Dosage for Children (over 1 year): 1-3 mg/kg/day, divided into 2-3 doses (morning and bedtime, 10-12 hours apart).
- Consult a doctor for children aged 1-3 years or special conditions.
Care Tips:
- Keep out of reach of children.
- Store below 25°C in the original package, away from moisture.
- Administer with food to reduce stomach upset.
- Consult a doctor if symptoms persist or worsen.
Notes:
- Do not take suppositories by mouth.
- Do not exceed the recommended dose.
- If you miss a dose, use it as soon as remembered unless it’s near the next dose.
- Do not double the dose to make up for a missed one.
Warnings and Precautions
- Stop use and consult a doctor immediately if you experience severe symptoms like sudden chest pain, breathing difficulty, leg/foot swelling, sudden weakness/numbness, vision loss, speech difficulty, or migraine-like headaches (signs of heart attack, heart failure, or stroke).
- Stop if signs of stomach/intestinal bleeding occur (e.g., blood in vomit, black/tarry stools).
- Avoid if allergic to diclofenac or other NSAIDs.
- Consult your doctor if taking medications like anticoagulants (e.g., warfarin), diuretics, lithium, methotrexate, cyclosporine, or ACE inhibitors.
- Contraindicated in severe renal, hepatic, or cardiac conditions.
- May cause rectal irritation or burning.
Possible Side Effects
- Common: Stomach pain, heartburn, nausea, vomiting, diarrhea, indigestion, gas, loss of appetite, headache, dizziness, skin rash, elevated liver enzymes, rectal irritation.
- Rare: Allergic reactions (rash, itching, peeling), gastrointestinal bleeding, cardiac/stroke symptoms.
- Stop use and consult a doctor if symptoms persist or severe symptoms occur.
Pregnancy and Breastfeeding Precautions
- Pregnancy: Not preferred, especially in the first and third trimesters. Consult your doctor.
- Breastfeeding: Use cautiously after consulting a doctor, as small amounts may pass into breast milk.
Non-Pharmacological Treatments to Reduce Pain
- Gentle Massage: Relieves muscle tension.
- Relaxation Techniques: Meditation or deep breathing to reduce pain.
- Physical Therapy: Improves mobility and reduces joint pain.
- Pet Therapy: Provides emotional and physical comfort.
- Gel Packs: Cold or hot packs to alleviate pain and inflammation.
- Rest: Avoid activities that worsen pain.
Frequently Asked Questions
Is Diclogesic safe for children?
Yes, for children over 1 year at 1-3 mg/kg/day, but consult a doctor for ages 1-3.
Can it be used with other medications?
Consult your doctor, especially if taking anticoagulants or heart medications.
What if I experience rectal irritation?
If irritation persists or severe symptoms occur, stop use and consult a doctor.
How long does it take to work?
Pain relief typically starts within hours, with continued improvement with regular use.
Can it be used during pregnancy?
Not preferred, especially in early or late pregnancy. Consult your doctor.
Additional Information
Diclogesic 12.5 mg 10 Suppositories is an effective solution for relieving pain, reducing fever, and treating inflammation in conditions like arthritis and muscle pain.
